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BioMed Research International
Volume 2013, Article ID 621604, 14 pages
Research Article

Evaluating Phylogenetic Informativeness as a Predictor of Phylogenetic Signal for Metazoan, Fungal, and Mammalian Phylogenomic Data Sets

1Department of Ecology and Evolutionary Biology, Yale University, 165 Prospect Street, New Haven, CT 06520, USA
2Department of Biostatistics, Yale University, 135 College Street, New Haven, CT 06520, USA
3Program in Computational Biology and Bioinformatics, 300 George Street, Yale University, New Haven, CT 06520, USA

Received 1 March 2013; Accepted 3 June 2013

Academic Editor: William Piel

Copyright © 2013 Francesc López-Giráldez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The supplementary material contains spreadsheets listing the genes for the empirical datasets used in the manuscript: FUNYBASE, TBR, DNA OrthoMaM, and AA OrthoMaM. Genes were ranked by the differential phylogenetic informativeness (DPI). DPI of each gene was evaluated quantitatively by integrating over the phylogenetic informativeness profile from the leaves to the root of the tree. Thus, DPI encompassed all branching points of the phylogenies, providing a summary of the relative informativeness of each gene to resolve all nodes in the phylogeny.

  1. Supplementary Material