In Vivo Evaluation of Ethanolic Extract of Zingiber officinale Rhizomes for Its Protective Effect against Liver Cirrhosis
Figure 4
Photomicrograph shows histopathological sections of the livers sampled from different experimental groups using an anti-PCNA antibody. (a) Normal control group was stained without adding the primary antibody and shows normal liver architecture with no signs of PCNA expression. (b) TAA control group showed many hepatocytes nuclei positive for PCNA monoclonal antibody. (c) TAA + silymarin treated rats with no expression of PCNA in hepatocytes. (d) TAA + 250 mg/kg of ERZO and (e) TAA + 500 mg/kg of ERZO group showed nearly normal liver architecture with no signs of PCNA expression (immunohistochemistry, 10x).
