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BioMed Research International
Volume 2014, Article ID 171892, 10 pages
http://dx.doi.org/10.1155/2014/171892
Research Article

Pathway-Driven Discovery of Rare Mutational Impact on Cancer

1Interdisciplinary Program in Bioinformatics, Seoul National University, San 56-1, Shilim-dong, Kwanak-gu, Seoul 151-742, Republic of Korea
2Samsung Genome Institute, Samsung Medical Center, Irwon-ro 81, Seoul 136-710, Republic of Korea
3Department of Statistics, Seoul National University, San 56-1, Shilim-dong, Kwanak-gu, Seoul 151-742, Republic of Korea

Received 31 January 2014; Accepted 14 March 2014; Published 4 May 2014

Academic Editor: FangXiang Wu

Copyright © 2014 TaeJin Ahn and Taesung Park. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplement Figure 1. The schematic diagram of the Pathway-driven discovery of rare mutational impact on cancer. A diagram describes the ‘while’ loop part in the pseudo-code.

Supplement Figure 2. Comparing mutated genes showing pathway level mRNA difference (Discovered) to genes reported as significantly mutated in breast cancer. Supplement table 1 provide detailed information.

Supplement Table 1. A list of mutated genes showing pathway level mRNA difference (Discovered) and genes previously reported as significantly mutated in breast cancer.

Supplement Table 2. A list of abbreviations (alphabetical order).

  1. Supplementary Figure 1
  2. Supplementary Figure 2
  3. Supplementary Table 1
  4. Supplementary Table 2