Metadherin, p50, and p65 Expression in Epithelial Ovarian Neoplasms: An Immunohistochemical Study

Table 2

Immunohistochemical expression of p50, p65, and MTDH in epithelial ovarian carcinomas (EOC), borderline ovarian tumours (BL), and benign ovarian cystadenomas (OC). The Mann Whitney 𝑈-test was used for the comparison of expression levels between the 3 groups of epithelial ovarian tumours.

p50 (nuclear and cytoplasmic)

Mann Whitney 𝑈-test (𝑃 values)

p65 (nuclear and cytoplasmic)

Mann Whitney 𝑈-test (𝑃 values)

AEG-1/MTDH; (nuclear and cytoplasmic)

Mann Whitney 𝑈-test (𝑃 values)

Immunoreactivity score

0

1

2

3

0

1

2

3

0

1

2

3

Epithelial ovarian carcinomas (EOC)

0/30

0/30

0/30

30/30

𝑃<0.001; (EOC versus BL); (EOC versus OC)

0/30

0/30

0/30

30/30

𝑃<0.001 (EOC versus OC); 𝑃>0.005; (OC versus BL)

0/30

0/30

0/30

30/30

𝑃<0.001 (EOC versus BL); (EOC versus OC)

Borderline tumours (BL)

2/15

0/15

0/15

13/15

𝑃<0.001 (BL versus OC)

1/15

0/15

0/15

14/15

𝑃<0.001 (BL versus OC)

1/15

0/15

0/15

14/15

𝑃<0.001 (BL versus OC)

Ovarian cystadenomas (OC)

28/31

0/31

0/31

3/31

28/31

0/31

0/31

3/31

30/31

0/31

0/31

1/31