Potential Probiotic Escherichia coli 16 Harboring the Vitreoscilla Hemoglobin Gene Improves Gastrointestinal Tract Colonization and Ameliorates Carbon Tetrachloride Induced Hepatotoxicity in Rats

Figure 4

Effect of probiotic E. coli 16 (pUC8:16gfp) encoding vgb gene on liver parameters: (a) serum glutamyl oxalacetate transaminase (SGOT) levels, (b) serum glutamyl pyruvate transaminase (SGPT) levels, (c) catalase activity, and (d) lipid peroxidation levels in different groups of rats treated with CCl₄. SGOT and SGPT activities were measured in plasma, whereas catalase activity and lipid peroxidation levels were measured in liver homogenates. ^∗∗∗∗𝑃<0.0001, ^∗∗∗𝑃<0.001, ^∗∗𝑃<0.01, and ^∗𝑃<0.05 compared to Group I (control without CC1₄ treatment). Values are expressed as mean ± SEM (𝑛=3 each group) and analysis was performed using one way ANOVA.

(a)

(b)

(c)

(d)