BioMed Research International / 2014 / Article / Fig 1

Review Article

Role of Nutrient-Sensing Signals in the Pathogenesis of Diabetic Nephropathy

Figure 1

Nutrient-sensing signal and diseases. The three nutrients-sensing pathways, mTOR, AMPK, and Sirt1, independently and coordinately regulate organ metabolism in multiple organs. Their alterations are involved in the pathogenesis of obesity-related and age-related diseases.

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