Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2014, Article ID 638902, 9 pages
http://dx.doi.org/10.1155/2014/638902
Research Article

Saccharin Sulfonamides as Inhibitors of Carbonic Anhydrases I, II, VII, XII, and XIII

1Department of Biothermodynamics and Drug Design, Institute of Biotechnology, Vilnius University, Graičiūno 8, LT-02241 Vilnius, Lithuania
2Department of Bioinformatics, Institute of Biotechnology, Vilnius University, Graičiūno 8, LT-02241 Vilnius, Lithuania
3Department of Organic Chemistry, Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV-1006, Latvia

Received 28 February 2014; Revised 28 April 2014; Accepted 28 May 2014; Published 3 September 2014

Academic Editor: Vincenzo Alterio

Copyright © 2014 Vaida Morkūnaitė et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [7 citations]

The following is the list of published articles that have cited the current article.

  • Vytautas Raskevicius, and Visvaldas Kairys, “Comparison of Performance of Docking, LIE, Metadynamics and QSAR in Predicting Binding Affinity of Benzenesulfonamides,” Current Computer-Aided Drug Design, vol. 11, no. 3, pp. 237–244, 2015. View at Publisher · View at Google Scholar
  • Brian P. Mahon, Cynthia O. Okoh, and Robert McKenna, “Targeting aggressive cancers with an artificial sweetener: could saccharin be a lead compound in anticancer therapy?,” Future Oncology, vol. 11, no. 15, pp. 2117–2119, 2015. View at Publisher · View at Google Scholar
  • Justina Kazokaitė, Ashok Aspatwar, Seppo Parkkila, and Daumantas Matulis, “An update on anticancer drug development and delivery targeting carbonic anhydrase IX,” PeerJ, vol. 5, pp. e4068, 2017. View at Publisher · View at Google Scholar
  • Mam Y. Mboge, Anusha Kota, Robert McKenna, and Susan C. Frost, “Biophysical, Biochemical, and Cell Based Approaches Used to Decipher the Role of Carbonic Anhydrases in Cancer and to Evaluate the Potency of Targeted Inhibitors,” International Journal of Medicinal Chemistry, vol. 2018, pp. 1–18, 2018. View at Publisher · View at Google Scholar
  • Srishti Singh, Carrie Lomelino, Mam Mboge, Susan Frost, and Robert McKenna, “Cancer Drug Development of Carbonic Anhydrase Inhibitors beyond the Active Site,” Molecules, vol. 23, no. 5, pp. 1045, 2018. View at Publisher · View at Google Scholar
  • Vaida Linkuvienė, Asta Zubrienė, Elena Manakova, Vytautas Petrauskas, Lina Baranauskienė, Audrius Zakšauskas, Alexey Smirnov, Saulius Gražulis, John E. Ladbury, and Daumantas Matulis, “Thermodynamic, kinetic, and structural parameterization of human carbonic anhydrase interactions toward enhanced inhibitor design,” Quarterly Reviews of Biophysics, vol. 51, 2018. View at Publisher · View at Google Scholar
  • Visvaldas Kairys, Kliment Olechnovič, Vytautas Raškevičius, and Daumantas Matulis, “In Silico Modeling of Inhibitor Binding to Carbonic Anhydrases,” Carbonic Anhydrase as Drug Target, pp. 215–232, 2019. View at Publisher · View at Google Scholar