Identification of a Novel Methylated Gene in Nasopharyngeal Carcinoma: TTC40

Table 4

Relationship between TTC40 methylation status and its expression.

		Methylation status			P value
		M (n = 3^a)	M/U (n = 24^b)	U (n = 14^c)
mRNA expression	+ (n = 23^d)	0	11	12	0.004
	− (n = 18^e)	3	13	2

M: full methylation, M/U: partial methylation, and U: unmethylation.
a: 3 NPC xenografts, b: 23 tumor biopsies + 1 nontumor, c: 9 tumor biopsies + 5 nontumors; d: 18 tumor biopsies + 5 nontumors; e: 3 NPC xenografts + 14 tumor biopsies + 1 nontumor. P value based on Fisher’s test.