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BioMed Research International
Volume 2014 (2014), Article ID 785382, 6 pages
Review Article

Plant Virus Expression Vector Development: New Perspectives

Cornell University, Ithaca, NY 14850, USA

Received 7 December 2013; Accepted 11 February 2014; Published 13 March 2014

Academic Editor: Chenming (Mike) Zhang

Copyright © 2014 Kathleen Hefferon. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Plant made biologics have elicited much attention over recent years for their potential in assisting those in developing countries who have poor access to modern medicine. Additional applications such as the stockpiling of vaccines against pandemic infectious diseases or potential biological warfare agents are also under investigation. Plant virus expression vectors represent a technology that enables high levels of pharmaceutical proteins to be produced in a very short period of time. Recent advances in research and development have brought about the generation of superior virus expression systems which can be readily delivered to the host plant in a manner that is both efficient and cost effective. This review presents recent innovations in plant virus expression systems and their uses for producing biologics from plants.