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BioMed Research International
Volume 2014, Article ID 878450, 14 pages
http://dx.doi.org/10.1155/2014/878450
Review Article

MicroRNAs: Promising New Antiangiogenic Targets in Cancer

1Molecular Oncology Laboratory, General University Hospital Research Fundation, Avda Tres Cruces 2, 46014 Valencia, Spain
2Department of Biotechnology, Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain
3Medical Oncology Department, General University Hospital, Avda Tres Cruces 2, 46014 Valencia, Spain
4Department of Medicine, Universitat de València, Avda Blasco Ibañez 15, 46010 Valencia, Spain

Received 6 June 2014; Accepted 18 July 2014; Published 14 August 2014

Academic Editor: Elisa Giovannetti

Copyright © 2014 Sandra Gallach et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [27 citations]

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  • Xin Dai, and Chalet Tan, “Combination of MicroRNA Therapeutics with Small-molecule Anticancer Drugs: Mechanism of Action and Co-delivery Nanocarriers,” Advanced Drug Delivery Reviews, 2014. View at Publisher · View at Google Scholar
  • Shaoyun Zhao, Zhe Gong, Jing Zhang, Xiaoge Xu, Peidong Liu, Wenjuan Guan, Lijun Jing, Tao Peng, Junfang Teng, and Yanjie Jia, “Elevated Serum MicroRNA Let-7c in Moyamoya Disease,” Journal of Stroke and Cerebrovascular Diseases, 2015. View at Publisher · View at Google Scholar
  • Li Zhang, C Alexander Valencia, Meng Chen, Pu-Jun Guan, Biao Dong, and Ling Pan, “Transfer of microRNAs by extracellular membrane microvesicles: a nascent crosstalk model in tumor pathogenesis, especially tumor cell-microenvironment interactions,” Journal of Hematology & Oncology, vol. 8, no. 1, 2015. View at Publisher · View at Google Scholar
  • Xingwang Yang, Xiaoming Wang, Hongyan Shen, Rong Deng, and Kecheng Xue, “Combination of miR-21 with Circulating Tumor Cells Markers Improve Diagnostic Specificity of Metastatic Breast Cancer,” Cell Biochemistry and Biophysics, 2015. View at Publisher · View at Google Scholar
  • Ke Zhao, Bao-Jun Chen, Zhi-Guo Chen, Yong-Jian Zhang, Di Xu, and Qi Liu, “Effect of miR-503 down-regulation on growth and invasion of esophagus carcinoma and related immune function,” Medical Science Monitor, vol. 21, pp. 3564–3569, 2015. View at Publisher · View at Google Scholar
  • G. R. Yin, Q. Wang, X. B. Zhang, and S. J. Wang, “Regulatory role of microRNA184 in osteosarcoma cells,” Genetics And Molecular Research, vol. 14, no. 4, pp. 14246–14252, 2015. View at Publisher · View at Google Scholar
  • Xiayu Wu, Neng Cao, Michael Fenech, and Xu Wang, “Role of Sirtuins in Maintenance of Genomic Stability: Relevance to Cancer and Healthy Aging,” DNA and Cell Biology, 2016. View at Publisher · View at Google Scholar
  • Montserrat Fitó, and Valentini Konstantinidou, “Nutritional Genomics and the Mediterranean Diet’s Effects on Human Cardiovascular Health,” Nutrients, vol. 8, no. 4, pp. 218, 2016. View at Publisher · View at Google Scholar
  • Pranjal Sarma, M. Janaki Ramaiah, Dhananjaya Pal, Utpal Bhadra, and Manika Pal Bhadra, “A novel bisindole-PBD conjugate inhibits angiogenesis by regulating STAT3 and VEGF in breast cancer cells,” Life Sciences, 2016. View at Publisher · View at Google Scholar
  • Vishal Chandra, Jong Joo Kim, Balraj Mittal, and Rajani Rai, “MicroRNA aberrations: An emerging field for gallbladder cancer management,” World Journal Of Gastroenterology, vol. 22, no. 5, pp. 1787–1799, 2016. View at Publisher · View at Google Scholar
  • David L Marks, Rachel Lo Olson, and Martin E. Fernandez-Zapico, “Epigenetic control of the tumor microenvironment,” Epigenomics, vol. 8, no. 12, pp. 1671–1687, 2016. View at Publisher · View at Google Scholar
  • Jiahui Zhao, Yongxing Wang, Yatong Chen, Yong Luo, and Yongguang Jiang, “Downregulated expression of miRNA-149 promotes apoptosis in side population cells sorted from the TSU prostate cancer cell line,” Oncology Reports, vol. 36, no. 5, pp. 2587–2600, 2016. View at Publisher · View at Google Scholar
  • Liang Zhang, and He Huang, “Targeting the Cancer Biomarker CD47: A Review on the Diverse Mechanisms of the CD47 Pathway in Cancer Treatment,” Anti-Cancer Agents In Medicinal Chemistry, vol. 16, no. 6, pp. 658–667, 2016. View at Publisher · View at Google Scholar
  • Paula Lopez-Serra, and Juan Sandoval, “MicroRNA Deregulation in Lung Cancer and Their Use as Clinical Tools,” Epigenetic Biomarkers and Diagnostics, pp. 539–555, 2016. View at Publisher · View at Google Scholar
  • Mohammad Mashreghi, Hassan Azarpara, Mahere R. Bazaz, Arash Jafari, Aria Masoudifar, Hamed Mirzaei, and Mahmoud R. Jaafari, “Angiogenesis biomarkers and their targeting ligands as potential targets for tumor angiogenesis,” Journal of Cellular Physiology, 2017. View at Publisher · View at Google Scholar
  • Judy R. van Beijnum, Elisa Giovannetti, Dennis Poel, Patrycja Nowak-Sliwinska, and Arjan W. Griffioen, “miRNAs: micro-managers of anticancer combination therapies,” Angiogenesis, 2017. View at Publisher · View at Google Scholar
  • Yun-Ping Li, Yuan-Qing Jie, Wei-Min Dai, Qiang Huang, Guo-Feng Yu, Xiao-Feng Fan, An Wu, and Dan-Dan Mao, “Effects of microRNA-26b on proliferation and invasion of glioma cells and related mechanisms,” Molecular Medicine Reports, vol. 16, no. 4, pp. 4165–4170, 2017. View at Publisher · View at Google Scholar
  • Nunzia Caporarello, Melania Olivieri, Mario Salmeri, Carmelina Daniela Anfuso, Gabriella Lupo, Martina Cristaldi, and Maria Teresa Cambria, “Classical VEGF, Notch and Ang Signalling in cancer angiogenesis, alternative approaches and future directions (review),” Molecular Medicine Reports, vol. 16, no. 4, pp. 4393–4402, 2017. View at Publisher · View at Google Scholar
  • Paul J. Davis, Matthew Leinung, and Shaker A. Mousa, “microRNAs and Angiogenesis,” Anti-Angiogenesis Strategies in Cancer Therapeutics, pp. 69–84, 2017. View at Publisher · View at Google Scholar
  • Sandra Gallach, Silvia Calabuig-Fariñas, Rafael Sirera, Miguel Martorell, Carlos Camps, Eloisa Jantus-Lewintre, David Montaner, Sergio Alonso, Ana Blasco, Marta Usó, and Ricardo Guijarro, “MicroRNA profiling associated with non-small cell lung cancer: Next generation sequencing detection, experimental validation, and prognostic value,” Oncotarget, vol. 8, no. 34, pp. 56143–56157, 2017. View at Publisher · View at Google Scholar
  • Nicola Silvestris, Domenico Ribatti, Stefania Tommasi, Oronzo Brunetti, Livia Fucci, Antonella Argentiero, Angela Calabrese, Ivana Cataldo, Katia Danza, Vito Longo, and Roberto Tamma, “Angiogenesis in adenosquamous cancer of pancreas,” Oncotarget, vol. 8, no. 56, pp. 95773–95779, 2017. View at Publisher · View at Google Scholar
  • Shaoying Yan, Xuefeng Shan, Ke Chen, Yuyang Liu, Gangfeng Yu, Qiuxu Chen, Tao Zeng, Liying Zhu, Hao Dang, Fengjiao Chen, Jiaji Ling, Ailong Huang, and Hua Tang, “LINC00052/miR-101-3p axis inhibits cell proliferation and metastasis by targeting SOX9 in hepatocellular carcinoma,” Gene, 2018. View at Publisher · View at Google Scholar
  • Salome Murinello, Yoshihiko Usui, Susumu Sakimoto, Maki Kitano, Edith Aguilar, H. Maura Friedlander, Amelia Schricker, Carli Wittgrove, Yoshihiro Wakabayashi, Michael I. Dorrell, Peter D. Westenskow, and Martin Friedlander, “ miR-30a-5p inhibition promotes interaction of Fas + endothelial cells and FasL + microglia to decrease pathological neovascularization and promote physiological angiogenesis ,” Glia, 2018. View at Publisher · View at Google Scholar
  • Mansi Arora, Deepak Kaul, Mansi Arora, and Deepak Kaul, “Cancer RNome: Evolution and Sustenance,” Cancer RNome: Nature & Evolution, pp. 113–242, 2018. View at Publisher · View at Google Scholar
  • Paola Ulivi, Matteo Canale, Alessandro Passardi, Giorgia Marisi, Martina Valgiusti, Giovanni Frassineti, Daniele Calistri, Dino Amadori, and Emanuela Scarpi, “Circulating Plasma Levels of miR-20b, miR-29b and miR-155 as Predictors of Bevacizumab Efficacy in Patients with Metastatic Colorectal Cancer,” International Journal of Molecular Sciences, vol. 19, no. 1, pp. 307, 2018. View at Publisher · View at Google Scholar
  • Bratati Mukherjee, Manjusha Dixit, and Ankit Tiwari, “MicroRNA key to angiogenesis regulation: MiRNA biology and therapy,” Current Cancer Drug Targets, vol. 18, no. 3, pp. 266–277, 2018. View at Publisher · View at Google Scholar
  • Vaishali Bhardwaj, and Abul Mandal, “Next-Generation Sequencing Reveals the Role of Epigallocatechin-3-Gallate in Regulating Putative Novel and Known microRNAs Which Target the MAPK Pathway in Non-Small-Cell Lung Cancer A549 Cells,” Molecules, vol. 24, no. 2, pp. 368, 2019. View at Publisher · View at Google Scholar