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BioMed Research International
Volume 2014, Article ID 934605, 15 pages
Review Article

Recent Trends of Polymer Mediated Liposomal Gene Delivery System

1Department of Physics, School of Basic and Applied Sciences, Galgotias University, Greater Noida 203201, India
2Department of Physics, Tokai University, Hiratsuka-Shi, Kanagawa 259-1292, Japan
3Institute for Skeletal Aging & Orthopedic Surgery, Hallym University-Chuncheon Sacred Heart Hospital, Chuncheon 200704, Republic of Korea
4Medical Biotechnology Division, School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu 632014, India
5Department of Bioinformatics, School of Computer Sciences, Galgotias University, Greater Noida 203201, India

Received 9 May 2014; Revised 15 July 2014; Accepted 15 July 2014; Published 27 August 2014

Academic Editor: Nagendra K. Kaushik

Copyright © 2014 Shyamal Kumar Kundu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Advancement in the gene delivery system have resulted in clinical successes in gene therapy for patients with several genetic diseases, such as immunodeficiency diseases, X-linked adrenoleukodystrophy (X-ALD) blindness, thalassemia, and many more. Among various delivery systems, liposomal mediated gene delivery route is offering great promises for gene therapy. This review is an attempt to depict a portrait about the polymer based liposomal gene delivery systems and their future applications. Herein, we have discussed in detail the characteristics of liposome, importance of polymer for liposome formulation, gene delivery, and future direction of liposome based gene delivery as a whole.