Research Article

Frequency and Clinical Implication of the R450H Mutation in the Thyrotropin Receptor Gene in the Japanese Population Detected by Smart Amplification Process 2

Figure 2

Detection of the R450H mutation in TSHR by the SmartAmp2 method using the clinical samples. (a) Amplification curves generated using whole blood from the participants by the SmartAmp2 method are shown. (b) Amplification curves generated using genomic DNA from the participants by the SmartAmp2 method are shown. (c) Direct sequencing results generated using genomic DNA of the participants are shown.
964635.fig.002a
(a)
964635.fig.002b
(b)
964635.fig.002c
(c)