Frequency and Clinical Implication of the R450H Mutation in the Thyrotropin Receptor Gene in the Japanese Population Detected by Smart Amplification Process 2

Table 2

Thyroid function in negative or positive cases of antithyroid antibodies.

	Antithyroid antibodies		𝑃
	Negative	Positive
Number*	122/195	34/78
Age (years)	63.7±10.7	66.3±7.8	0.063
BMI (kg/m^2)	22.9 ± 2.8	23.0 ± 2.7	0.605
TSH (𝜇U/mL)	1.69 ± 0.93	2.58 ± 3.92	<0.001
Number of cases with elevated TSH levels above reference range	0	7
FT3 (pg/mL)	3.12 ± 0.49	3.08 ± 0.48	0.419
FT4 (ng/dL)	1.05 ± 0.16	1.04 ± 0.17	0.349

∗Men/women. Data are expressed as mean ± SD.