MicroRNAs as Potential Biomarkers in Cancer: Opportunities and Challenges

Table 3

Potential miRNAs biomarkers for types of cancers in blood and other body fluids.

Cancer	Samples	miRNAs biomarkers	Expression	Reference
Glioblastoma	Serum	miR-15b, -23a, -133a, -150, -197, -497	Up	[158]
	Plasma	miR-128, -342-3p	Down	[30]
	CSF	miR-21, -17-5p, -200	Up	[30]
Head and neck	Plasma	miR-31, -10b, -24, -181, -184	Up	[87]
	Saliva	miR-31	Up	[87]
		miR-200a, -125a	Down	[87]
Breast cancer	Serum	miR-373, -155	Up	[159]
		miR-34a, -17	Down	[159]
		miR-222, -103, -23a, -29a, -23b, -24, -25	Up	[160]
	Plasma	miR-148b, -376c, -409-3p, -801	Up	[80]
Lung cancer	Serum	miR-21-3p, -205-5p, -205-3p, -141, -200c	Up	[92]
		miR-21, -24, -205, -30d	Up	[93]
	Plasma	miR-21, -155	Up	[114]
		miR-145	Down	[114]
	Exosome	miR-17-3p, -21, -106a, -146, -155, -191,-192, -203, -205, -210, -212, -214	Up	[161]
	Sputum	miR-205, -210, -708	Up	[90]
Liver cancer	Serum	miR-122	Up	[162]
		miR-500	Up	[163]
		miR-21, -122, -223	Up	[164]
		miR-21, -1, -25, -92a, -206, -375, let-7f	Up	[165]
		miR-16	Down	[166]
Gastric cancer	Serum	miR-221, -376c, -744	Up	[167]
		miR-1, -20a, -27a, -34, -423-5p	Up	[168]
	Plasma	miR-106b, -20a, -221	Up	[81]
		miR-21, -223, -218	Up	[169]
		miR-451, -486	Down	[170]
Pancreatic cancer	Serum	miR-21, -100, -155	Up	[171]
		miR-203, -369-5p, -376a, -375	Up	[172]
	Plasma	miR-21, -210, -155, -196a	Up	[82, 173]
	Exosome	miR-21, -17-5p	Up	[174]
Colorectal cancer	Serum	miR-29a	Up	[175]
	Plasma	miR-17-3p, -92	Up	[68]
		miR-92a, -29a	Up	[176]
		miR-27b, -148a, -326	Up	[177]
		miR-221	Up	[178]
		miR-15b, -17	Up	[179]
Ovarian cancer	Serum	miR-21, -92, -93, -126, -29a	Up	[131]
		miR-155, -127, -99b	Down	[131]
	Plasma	miR-205	Up	[180]
		let-7f	Down	[180]
	Exosome	miR-21, -141, -200a/b/c, -203, -205, -214	Up	[84]
Prostate cancer	Serum	miR-26a-1, -141, -375	Up	[181]
		miR-16, -195, -26a, let7i	Up	[128]
		miR-20b, -874, -1274a, -1207-5p, -93, -106a	Up	[182]
		miR-223, -26b, -30c, -24	Down	[182]
	Exosome	miR-107, -574-3p	Up	[85]
Bladder	Blood	miR-129, -133b	Up	[183]
		miR-26b-5p, -144-5p, -374-5p	Up	[184]
		miR-378g, -942, -106a-5p, -142-3p, -374a	Up	[185]
	Urine	miR-18a, -25, -187	Up	[89]
		miR-142-3p, -140-5p, -204	Down	[89]
		miR-214	Up	[91]
		miR-200, -155, -192, -205	Up	[186]
Large B-cell lymphoma	Serum	miR-21, -155, -210	Up	[73]
		miR-15a, -16-1, -29c, -155	Up	[187]
		miR-34a	Down	[187]
Leukemia	Serum	miR-181b-5p, -10a-5p, -93-5p	Up	[188]
		miR-129-5p, -155-5p, -320d	Up	[188]
		miR-29c, -223	Down	[189]