Research Article

Genetic Diversity of Mycobacterium tuberculosis Complex Isolated from Tuberculosis Patients in Bahir Dar City and Its Surroundings, Northwest Ethiopia

Table 3

Spoligotype patterns of 45 orphan strains and their corresponding lineages/sublineages identified from a total of 168 Mycobacterium tuberculosis complex isolates collected in tuberculosis patients in the Bahir Dar region.

SITIsolates with similar patternSITVIT2 lineage/sublineageCBN lineageOctal numberBinary format

Orphan1TEA776603777760771
Orphan1TEA777737347760771
Orphan1TEA276777777760771
Orphan1T3-ETHEA777002377420771
Orphan1T2EA777777403760731
Orphan1EAIEA777760370000000
Orphan1EAIEA777770370000000
Orphan1T3-ETHEA777002377760731
Orphan1T1-RUS2EA770002001760771
Orphan1EAIEA777760370000000
Orphan1TEA276777737760771
Orphan1T-H37RvEA777777444760771
Orphan1X1EA400002757760771
Orphan1T2EA777777403760731
Orphan1Manu2EA577747777767771
Orphan1H3EA777737377720731
Orphan1Manu2EA777777774363771
Orphan1LAM3EA760002007760771
Orphan1AFRIEAI700022044037771
Orphan1UnknownEAI000022000003771
Orphan1CASEAI700002000000771
Orphan1PINI2EAI400200000000751
Orphan1H2EAI700000004037771
Orphan1CAS1-DelhiEAI703602040003571
Orphan1PINI2EAI000022000003771
Orphan1HEAI000002004020631
Orphan1CAS1-DelhiEAI703677740003571
Orphan1CASEAI703777700001171
Orphan1CAS1-DelhiEAI703622040003571
Orphan1AFRIM. africanum700022007177771
Orphan1AFRIM. africanum700002044177771
Orphan1AFRIM. africanum700020044177771
Orphan2AFRIM. africanum700002004177771
Orphan1AFRIM. africanum700002004177771
Orphan1AFRIM. africanum771022044177771
Orphan1AFRIM. africanum700002004177771
Orphan1AFRIM. africanum700002007177771
Orphan1AFRIM. africanum700002007177771
Orphan1AFRIM. africanum700022004177771
Orphan1AFRIM. africanum700022047177771
Orphan1Manu1IO773777747777771
Orphan1Manu2IO773777744203771
Orphan1Manu1IO753777747777771
Orphan1Manu1IO717777777777771
Orphan1EAIIO717777776003771

CBN: conformal Bayesian network; unknown: designates patterns with signatures that do not belong to any of the major lineages/sublineages described in the SITVIT2 database. Forty-five of the total 89 strains were identified as orphan strains in the present study and shown in Table 3. The orphan strains belonged to four lineages including Euro-American, East-African Indian, M. africanum, and Indo-Oceanic lineages.