Genetic Diversity of Mycobacterium tuberculosis Complex Isolated from Tuberculosis Patients in Bahir Dar City and Its Surroundings, Northwest Ethiopia
Table 3
Spoligotype patterns of 45 orphan strains and their corresponding lineages/sublineages identified from a total of 168 Mycobacterium tuberculosis complex isolates collected in tuberculosis patients in the Bahir Dar region.
SIT
Isolates with similar pattern
SITVIT2 lineage/sublineage
CBN lineage
Octal number
Binary format
Orphan
1
T
EA
776603777760771
Orphan
1
T
EA
777737347760771
Orphan
1
T
EA
276777777760771
Orphan
1
T3-ETH
EA
777002377420771
Orphan
1
T2
EA
777777403760731
Orphan
1
EAI
EA
777760370000000
Orphan
1
EAI
EA
777770370000000
Orphan
1
T3-ETH
EA
777002377760731
Orphan
1
T1-RUS2
EA
770002001760771
Orphan
1
EAI
EA
777760370000000
Orphan
1
T
EA
276777737760771
Orphan
1
T-H37Rv
EA
777777444760771
Orphan
1
X1
EA
400002757760771
Orphan
1
T2
EA
777777403760731
Orphan
1
Manu2
EA
577747777767771
Orphan
1
H3
EA
777737377720731
Orphan
1
Manu2
EA
777777774363771
Orphan
1
LAM3
EA
760002007760771
Orphan
1
AFRI
EAI
700022044037771
Orphan
1
Unknown
EAI
000022000003771
Orphan
1
CAS
EAI
700002000000771
Orphan
1
PINI2
EAI
400200000000751
Orphan
1
H2
EAI
700000004037771
Orphan
1
CAS1-Delhi
EAI
703602040003571
Orphan
1
PINI2
EAI
000022000003771
Orphan
1
H
EAI
000002004020631
Orphan
1
CAS1-Delhi
EAI
703677740003571
Orphan
1
CAS
EAI
703777700001171
Orphan
1
CAS1-Delhi
EAI
703622040003571
Orphan
1
AFRI
M. africanum
700022007177771
Orphan
1
AFRI
M. africanum
700002044177771
Orphan
1
AFRI
M. africanum
700020044177771
Orphan
2
AFRI
M. africanum
700002004177771
Orphan
1
AFRI
M. africanum
700002004177771
Orphan
1
AFRI
M. africanum
771022044177771
Orphan
1
AFRI
M. africanum
700002004177771
Orphan
1
AFRI
M. africanum
700002007177771
Orphan
1
AFRI
M. africanum
700002007177771
Orphan
1
AFRI
M. africanum
700022004177771
Orphan
1
AFRI
M. africanum
700022047177771
Orphan
1
Manu1
IO
773777747777771
Orphan
1
Manu2
IO
773777744203771
Orphan
1
Manu1
IO
753777747777771
Orphan
1
Manu1
IO
717777777777771
Orphan
1
EAI
IO
717777776003771
CBN: conformal Bayesian network; unknown: designates patterns with signatures that do not belong to any of the major lineages/sublineages described in the SITVIT2 database. Forty-five of the total 89 strains were identified as orphan strains in the present study and shown in Table 3. The orphan strains belonged to four lineages including Euro-American, East-African Indian, M. africanum, and Indo-Oceanic lineages.