BioMed Research International / 2015 / Article / Tab 2

Research Article

Network Comparison of Inflammation in Colorectal Cancer and Alzheimer’s Disease

Table 2

KEGG pathways associated with the 16 oppositely expressed common genes (in Table 1) in the AD and the CRC networks. From the AD and the CRC networks, pathway information of the 16 genes was obtained. The 16 genes were inversely expressed in the pathways between the AD and the CRC networks.

Gene symbolsPathwaysCRC (GSE4107)AD (GSE12685)AD (GSE1297)

PTPN6hsa04662_B_cell_receptor_signaling_pathway; hsa04630_Jak-STAT_signaling_pathway; hsa05140_LeishmaniasisUpDownDown
IRAK3hsa04722_Neurotrophin_signaling_pathway
FLT3hsa05221_Acute_myeloid_leukemia
DDIT3hsa04010_MAPK_signaling_pathway
FAShsa04115_p53_signaling_pathway; hsa04650_Natural_killer_cell_mediated_cytotoxicity
IRF3hsa04622_RIG-I-like_receptor_signaling_pathway; hsa04623_Cytosolic_DNA-sensing_pathway
CCR6hsa04060_Cytokine-cytokine_receptor_interaction; hsa04062_Chemokine_signaling_pathway
CD28hsa04660_T_cell_receptor_signaling_pathway; hsa05416_Viral_myocarditis
FCER1Ghsa04650_Natural_killer_cell_mediated_cytotoxicity
NGFRhsa04722_Neurotrophin_signaling_pathway
FN1hsa04512_ECM-receptor_interaction

BADhsa04510_Focal_adhesion; hsa05223_Non-small_cell_lung_cancer; hsa05210_Colorectal_cancerDownUpUp
CD36hsa03320_PPAR_signaling_pathway; hsa04512_ECM-receptor_interaction
PPARDhsa05221_Acute_myeloid_leukemia; hsa04310_Wnt_signaling_pathway
ABL1hsa04012_ErbB_signaling_pathway; hsa04722_Neurotrophin_signaling_pathway
EGFRhsa05214_Glioma; hsa04012_ErbB_signaling_pathway

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