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BioMed Research International
Volume 2015, Article ID 382745, 12 pages
http://dx.doi.org/10.1155/2015/382745
Research Article

RNA-Based TWIST1 Inhibition via Dendrimer Complex to Reduce Breast Cancer Cell Metastasis

1Department of Neurosciences, City of Hope Beckman Research Institute, 1500 East Duarte Road, Duarte, CA 91010, USA
2Irell & Manella Graduate School of Biological Sciences, City of Hope Beckman Research Institute, 1500 East Duarte Road, Duarte, CA 91010, USA
3Division of Comparative Medicine, City of Hope Beckman Research Institute, 1500 East Duarte Road, Duarte, CA 91010, USA
4Department of Biological Sciences, California State University, Los Angeles, 5151 State University Drive, Los Angeles, CA 90032-8201, USA

Received 20 June 2014; Revised 31 December 2014; Accepted 31 December 2014

Academic Editor: Eric W.-F. Lam

Copyright © 2015 James Finlay et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [27 citations]

The following is the list of published articles that have cited the current article.

  • Zhu-Gen Cao, Xiao-Bing Qin, Fang-Fang Liu, and Lei-Lei Zhou, “Tryptophan-induced pathogenesis of breast cancer,” African Health Sciences, vol. 15, no. 3, pp. 982–985, 2015. View at Publisher · View at Google Scholar
  • Tânia Filipa S. Mendes, Leon D. Kluskens, and Lígia Raquel Rodrigues, “Triple Negative Breast Cancer: Nanosolutions for a Big Challenge,” Advanced Science, 2015. View at Publisher · View at Google Scholar
  • Prashant Kesharwani, Sanjeev Banerjee, Umesh Gupta, Mohd Cairul Iqbal Mohd Amin, Subhash Padhye, Fazlul H. Sarkar, and Arun K. Iyer, “PAMAM dendrimers as promising nanocarriers for RNAi therapeutics,” Materials Today, 2015. View at Publisher · View at Google Scholar
  • James Finlay, Cai M. Roberts, Juyao Dong, Jeffrey I. Zink, Fuyuhiko Tamanoi, and Carlotta A. Glackin, “Mesoporous silica nanoparticle delivery of chemically modified siRNA against TWIST1 leads to reduced tumor burden,” Nanomedicine: Nanotechnology, Biology and Medicine, 2015. View at Publisher · View at Google Scholar
  • Can Sarisozen, Giuseppina Salzano, and Vladimir P. Torchilin, “Recent advances in siRNA delivery,” Biomolecular Concepts, vol. 6, no. 5-6, pp. 321–341, 2015. View at Publisher · View at Google Scholar
  • Anuradha Subramanian, Amrutha Manigandan, A. Sivashankari, and Swaminathan Sethuraman, “Development of nanotheranostics against metastatic breast cancer – a focus on the biology & mechanistic apaaproaches,” Biotechnology Advances, 2015. View at Publisher · View at Google Scholar
  • Qingxin Mu, Hui Wang, and Miqin Zhang, “Nanoparticles for imaging and treatment of metastatic breast cancer,” Expert Opinion on Drug Delivery, pp. 1–14, 2016. View at Publisher · View at Google Scholar
  • Michelle A. Tran, Joana Loeza, Thanh H. Dellinger, Carlotta A. Glackin, Cai M. Roberts, Mary C. Pitruzzello, Wei Wen, and Gil Mor, “TWIST1 drives cisplatin resistance and cell survival in an ovarian cancer model, via upregulation of GAS6, L1CAM, and Akt signalling,” Scientific Reports, vol. 6, 2016. View at Publisher · View at Google Scholar
  • Hong Ren, Peizhun Du, Zongyu Ge, Yiting Jin, Di Ding, Xiuping Liu, and Qiang Zou, “TWIST1 and BMI1 in Cancer Metastasis and Chemoresistance,” Journal Of Cancer, vol. 7, no. 9, pp. 1074–1080, 2016. View at Publisher · View at Google Scholar
  • James T. DeLigio, Grace Lin, Charles E. Chalfant, and Margaret A. Park, “Splice variants of cytosolic polyadenylation element–binding protein 2 (CPEB2) differentially regulate pathways linked to cancer metastasis,” Journal of Biological Chemistry, vol. 292, no. 43, pp. 17909–17918, 2017. View at Publisher · View at Google Scholar
  • Stefan Werner, Arnulf Stenzl, Klaus Pantel, and Tilman Todenhöfer, “Expression of Epithelial Mesenchymal Transition and Cancer Stem Cell Markers in Circulating Tumor Cells,” Isolation and Molecular Characterization of Circulating Tumor Cells, vol. 994, pp. 205–228, 2017. View at Publisher · View at Google Scholar
  • Cai M. Roberts, Sophia Allaf Shahin, Wei Wen, James B. Finlay, Juyao Dong, Ruining Wang, Thanh H. Dellinger, Jeffrey I. Zink, Fuyuhiko Tamanoi, and Carlotta A. Glackin, “Nanoparticle delivery of siRNA against TWIST to reduce drug resistance and tumor growth in ovarian cancer models,” Nanomedicine: Nanotechnology, Biology and Medicine, vol. 13, no. 3, pp. 965–976, 2017. View at Publisher · View at Google Scholar
  • Aishwarya Singh, Piyush Trivedi, and Narendra Kumar Jain, “Advances in siRNA delivery in cancer therapy,” Artificial Cells, Nanomedicine, and Biotechnology, pp. 1–10, 2017. View at Publisher · View at Google Scholar
  • Cai M. Roberts, Sophia A. Shahin, Joana Loeza, Thanh H. Dellinger, John C. Williams, and Carlotta A. Glackin, “Disruption of TWIST1-RELA binding by mutation and competitive inhibition to validate the TWIST1 WR domain as a therapeutic target,” BMC Cancer, vol. 17, no. 1, 2017. View at Publisher · View at Google Scholar
  • Giulia Bottai, Marta Truffi, Fabio Corsi, and Libero Santarpia, “Progress in nonviral gene therapy for breast cancer and what comes next?,” Expert Opinion on Biological Therapy, vol. 17, no. 5, pp. 595–611, 2017. View at Publisher · View at Google Scholar
  • Jenny G Parvani, and Mark W Jackson, “Silencing the roadblocks to effective triple-negative breast cancer treatments by siRNA nanoparticles,” Endocrine-Related Cancer, vol. 24, no. 4, pp. R81–R97, 2017. View at Publisher · View at Google Scholar
  • Volha Dzmitruk, Evgeny Apartsin, Aliaksei Ihnatsyeu-Kachan, Viktar Abashkin, Dzmitry Shcharbin, and Maria Bryszewska, “Dendrimers Show Promise for siRNA and microRNA Therapeutics,” Pharmaceutics, vol. 10, no. 3, pp. 126, 2018. View at Publisher · View at Google Scholar
  • Udo Jeschke, Alexandra Kölbl, Ulrich Andergassen, Kristina Schlenk, and Harald Sommer, “Epithelial-mesenchymal transition was identified as a potential marker for breast cancer aggressiveness using reverse transcription-quantitative polymerase chain reaction,” Molecular Medicine Reports, vol. 18, no. 2, pp. 1733–1739, 2018. View at Publisher · View at Google Scholar
  • Sandra Sanchez-Salcedo, Carlotta A. Glackin, Maria Vallet-Regí, Sophia Allaf Shahin, and Jeffrey I. Zink, “Mesoporous core-shell silica nanoparticles with anti-fouling properties for ovarian cancer therapy,” Chemical Engineering Journal, vol. 340, pp. 114–124, 2018. View at Publisher · View at Google Scholar
  • Andrei M. Mikheev, Svetlana A. Mikheeva, Liza J. Severs, Cory C. Funk, Lei Huang, José L. McFaline-Figueroa, Jeanette Schwensen, Cole Trapnell, Nathan D. Price, Stephen Wong, and Robert C. Rostomily, “Targeting TWIST1 through loss of function inhibits tumorigenicity of human glioblastoma,” Molecular Oncology, 2018. View at Publisher · View at Google Scholar
  • Sophia A. Shahin, Ruining Wang, Shirleen I. Simargi, Altagracia Contreras, Liliana Parra, Louise Qu, Wei Wen, Thanh Dellinger, Juli Unternaehrer, Fuyuhiko Tamanoi, Jeffrey I. Zink, and Carlotta A. Glackin, “Hyaluronic acid conjugated nanoparticle delivery of siRNA against TWIST reduces tumor burden and enhances sensitivity to cisplatin in ovarian cancer,” Nanomedicine: Nanotechnology, Biology and Medicine, 2018. View at Publisher · View at Google Scholar
  • Ida Franiak-Pietryga, Barbara Ziemba, Bradley Messmer, and Dorota Skowronska-Krawczyk, “Dendrimers as Drug Nanocarriers: The Future of Gene Therapy and Targeted Therapies in Cancer,” Dendrimers - Fundamentals and Applications, 2018. View at Publisher · View at Google Scholar
  • Arjaree Jobdeedamrong, Ratchapol Jenjob, and Daniel Crespy, “Encapsulation and Release of Essential Oils in Functional Silica Nanocontainers,” Langmuir, 2018. View at Publisher · View at Google Scholar
  • Tamkin Ahmadzada, Glen Reid, and David R. McKenzie, “Fundamentals of siRNA and miRNA therapeutics and a review of targeted nanoparticle delivery systems in breast cancer,” Biophysical Reviews, 2018. View at Publisher · View at Google Scholar
  • Carlotta A. Glackin, “Nanoparticle Delivery of TWIST Small Interfering RNA and Anticancer Drugs: A Therapeutic Approach for Combating Cancer,” 2018. View at Publisher · View at Google Scholar
  • Rebecca Kohnken, Betina McNeil, Jing Wen, Kathleen McConnell, Leah Grinshpun, Ashleigh Keiter, Luxi Chen, Basem William, Pierluigi Porcu, and Anjali Mishra, “Preclinical Targeting of MicroRNA-214 in Cutaneous T-Cell Lymphoma,” Journal of Investigative Dermatology, 2019. View at Publisher · View at Google Scholar
  • Christopher Halbur, Niharika Choudhury, Michael Chen, Jun Hyuk Kim, and Eun Ji Chung, “siRNA-Conjugated Nanoparticles to Treat Ovarian Cancer,” SLAS TECHNOLOGY: Translating Life Sciences Innovation, pp. 247263031881666, 2019. View at Publisher · View at Google Scholar