Experimental Protoporphyria: Effect of Bile Acids on Liver Damage Induced by Griseofulvin

Figure 5

Effect of bile acids on GST activity and on CYP levels. (a) GST, mean control value: 22.77 ± 1.20 μnmol/mg protein (); (b) CYP levels. Results in (a) are expressed as percentage of the corresponding control value taken as 100%; in (b) data are expressed as mean values ± S.D. and significance of differences between group treated and control group. and , significance of differences between the groups treated with Gris plus bile acid with respect to the group receiving only Gris. and , significance of differences between the group treated with Gris plus bile acid with respect to the group receiving only bile acid. More experimental details are described in legend of Figure 2.

(a)

(b)