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BioMed Research International
Volume 2015, Article ID 490295, 9 pages
Research Article

TRAF1/C5 but Not PTPRC Variants Are Potential Predictors of Rheumatoid Arthritis Response to Anti-Tumor Necrosis Factor Therapy

1Rheumatology Research Unit, Instituto de Medicina Molecular, Edifício Egas Moniz, Faculdade de Medicina da Universidade de Lisboa, Avenida Egas Moniz, 1649-028 Lisbon, Portugal
2Rheumatology Department, Hospital de Santa Maria (CHLN), Lisbon Academic Medical Centre, 1649-035 Lisbon, Portugal
3Division of Rheumatology, Allergy and Immunology, Section of Clinical Sciences, Brigham and Women’s Hospital, Boston, MA 02115, USA
4Rheumatology Department, Hospital Garcia de Orta, 2805-267 Almada, Portugal
5SEEBMO, Hospital de Santo Espirito da Ilha Terceira, Azores, 9700-049 Angra do Heroísmo, Portugal
6Genetics & Arthritis Research Group (GARG), Institute for Molecular and Cell Biology (IBMC), 4150-180 Oporto, Portugal
7Rheumatology Department, Conde de Bertiandos Hospital (ULSAM), 4990-041 Ponte de Lima, Portugal
8Instituto Português de Reumatologia, Lisbon, Portugal
9Rheumatology Department, Centro Hospitalar da Universidade de Coimbra, 3000-076 Coimbra, Portugal
10Rheumatology Department, Virgen de las Nieves University Hospital, Granada, Spain
11Rheumatology Department, University of Medicine and Pharmacy “Iuliu Hatieganu”, Cluj-Napoca, Romania
12CEDOC, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal
13Rheumatology Department, Hospital de Egas Moniz (CHLO), 1349-019 Lisbon, Portugal
14Genomic Oncology Area, GENYO Centre for Genomics and Oncological Research, Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, Granada, Spain
15The Broad Institute of Harvard and MIT, Cambridge, MA, USA
16Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Boston, MA, USA

Received 25 July 2014; Accepted 26 November 2014

Academic Editor: María E. Esteban

Copyright © 2015 Helena Canhão et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Helena Canhão, Ana Maria Rodrigues, Maria José Santos, et al., “TRAF1/C5 but Not PTPRC Variants Are Potential Predictors of Rheumatoid Arthritis Response to Anti-Tumor Necrosis Factor Therapy,” BioMed Research International, vol. 2015, Article ID 490295, 9 pages, 2015.