Research Article

Sustained Macrophage Infiltration upon Multiple Intra-Articular Injections: An Improved Rat Model of Rheumatoid Arthritis for PET Guided Therapy Evaluation

Figure 8

Ex vivo tissue distribution of (R)-[11C] PK11195 at 1 h after injection in rats of (a) no boost groups A (6 d) and B (28 d); (b) no boost group B (28 d), boost groups C (19 d), and D (28 d). Results are expressed as percentage of the injected dose per gram (%ID/g ± SD).
(a)
(b)