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BioMed Research International
Volume 2015, Article ID 697958, 13 pages
Research Article

Mass Spectral Profile for Rapid Differentiating Beta-Lactams from Their Ring-Opened Impurities

1School of Life Science, Beijing Institute of Technology, 5 Zhongguancun Street, South Haidian District, Beijing 100081, China
2Neuroscience Research Institute, Health Science Center, Peking University, Beijing 100191, China
3National Institutes for Food and Drug Control, Beijing 100050, China

Received 13 June 2014; Revised 1 September 2014; Accepted 7 October 2014

Academic Editor: Haiteng Deng

Copyright © 2015 Hecheng Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Material: For the sake of better understanding the different CID profiles of beta-lactams and their ring-opened impurities, additional information about the CID reactions and CID spectra of some compound, as well as the identification of impurities in cefdinir and cefaclor, were provided as “Supplementary Material”.

  1. Supplementary Material