Gene Expression-Genotype Analysis Implicates GSDMA, GSDMB, and LRRC3C as Contributors to Inflammatory Bowel Disease Susceptibility

Figure 4

Association between rs2872507 genotype and intestinal GSDMB expression in non-IBD patients. Genotype (A is the IBD risk allele) versus the relative quantity (RQ) of GSDMB expression in intestinal biopsies from noninflamed ileal non-IBD mucosa ((a) = 6, = 11, = 7; = −0.59, = 2.38 × 10⁻³) or noninflamed colonic non-IBD mucosa ((b) = 10, = 15, = 8; = −0.58, = 3.69 × 10⁻⁴).

(a)

(b)