BioMed Research International / 2015 / Article / Tab 1

Research Article

Gene Expression-Genotype Analysis Implicates GSDMA, GSDMB, and LRRC3C as Contributors to Inflammatory Bowel Disease Susceptibility

Table 1

Clinical characteristics of participants.

IBD
( = 52)
Non-IBD
( = 33)

Disease (CD/UC/IBDU)21/29/2
Disease (non-IBD)a
Gender (male/female)23/2913/20
Age (years)40 (18–77)49 (20–82)
Smoker (yes/previous/no/no data)6/5/35/63/2/23/5
Immune-modulating drugs
 Aminosalicylates240
 Thiopurines170
 Corticosteroids170
 Anti-TNF-α-antibodies61
 Methotrexate21
 Tacrolimus21
 None1033

Patients were referred for investigation of gastrointestinal symptoms (e.g., diarrhea, fecal blood, or abdominal pain) or for screening for colorectal adenomas with the following findings: diverticulosis ( = 4), polyps ( = 5), low-grade dysplasia adenomas ( = 2), colorectal cancer ( = 2), hemorrhoids ( = 3), radiation proctitis ( = 1), or without pathological findings ( = 19). There were two instances of simultaneous diverticulosis and polyps and one instance of simultaneous diverticulosis and hemorrhoids.
Median (range) values are given.