Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2015, Article ID 859456, 9 pages
http://dx.doi.org/10.1155/2015/859456
Research Article

Microstereolithography-Based Fabrication of Anatomically Shaped Beta-Tricalcium Phosphate Scaffolds for Bone Tissue Engineering

1Department of Orthopaedic Surgery, Sino-Russian Institute of Hard Tissue Development and Regeneration, Harbin Medical University, Nangang, Harbin 150086, China
2Department of Bioengineering, University of Tokyo, Bunkyō, Tokyo 113-8656, Japan
3Department of Mechanical Engineering, Tokyo Denki University, Adachi, Tokyo 101-8457, Japan
4Center for Disease Biology and Integrative Medicine, University of Tokyo, Bunkyō, Tokyo 113-8656, Japan

Received 20 April 2015; Revised 3 August 2015; Accepted 3 August 2015

Academic Editor: Vladimir S. Komlev

Copyright © 2015 Dajiang Du et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. Polo-Corrales, M. Latorre-Esteves, and J. E. Ramirez-Vick, “Scaffold design for bone regeneration,” Journal of Nanoscience and Nanotechnology, vol. 14, no. 1, pp. 15–56, 2014. View at Publisher · View at Google Scholar · View at Scopus
  2. A. Oryan, S. Alidadi, A. Moshiri, and N. Maffulli, “Bone regenerative medicine: classic options, novel strategies, and future directions,” Journal of Orthopaedic Surgery and Research, vol. 9, no. 1, article 18, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. P. Habibovic and K. de Groot, “Osteoinductive biomaterials—properties and relevance in bone repair,” Journal of Tissue Engineering and Regenerative Medicine, vol. 1, no. 1, pp. 25–32, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. D.-W. Cho and H.-W. Kang, “Microstereolithography-based computer-aided manufacturing for tissue engineering,” Methods in Molecular Biology, vol. 868, pp. 341–356, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. S. V. Dorozhkin and M. Epple, “Biological and medical significance of calcium phosphates,” Angewandte Chemie—International Edition, vol. 41, no. 17, pp. 3130–3146, 2002. View at Google Scholar · View at Scopus
  6. P. X. Lan, J. W. Lee, Y.-J. Seol, and D.-W. Cho, “Development of 3D PPF/DEF scaffolds using micro-stereolithography and surface modification,” Journal of Materials Science: Materials in Medicine, vol. 20, no. 1, pp. 271–279, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. K.-W. Lee, S. Wang, B. C. Fox, E. L. Ritman, M. J. Yaszemski, and L. Lu, “Poly(propylene fumarate) bone tissue engineering scaffold fabrication using stereolithography: effects of resin formulations and laser parameters,” Biomacromolecules, vol. 8, no. 4, pp. 1077–1084, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. I. K. Kwon and T. Matsuda, “Photo-polymerized microarchitectural constructs prepared by microstereolithography (μSL) using liquid acrylate-end-capped trimethylene carbonate-based prepolymers,” Biomaterials, vol. 26, no. 14, pp. 1675–1684, 2005. View at Publisher · View at Google Scholar · View at Scopus
  9. M. N. Cooke, J. P. Fisher, D. Dean, C. Rimnac, and A. G. Mikos, “Use of stereolithography to manufacture critical-sized 3D biodegradable scaffolds for bone ingrowth,” Journal of Biomedical Materials Research - Part B Applied Biomaterials, vol. 64, no. 2, pp. 65–69, 2003. View at Google Scholar · View at Scopus
  10. J. W. Lee, P. X. Lan, B. Kim, G. Lim, and D.-W. Cho, “Fabrication and characteristic analysis of a poly(propylene fumarate) scaffold using micro-stereolithography technology,” Journal of Biomedical Materials Research Part B: Applied Biomaterials, vol. 87, no. 1, pp. 1–9, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. Y.-J. Seol, D. Y. Park, J. Y. Park, S. W. Kim, S. J. Park, and D.-W. Cho, “A new method of fabricating robust freeform 3D ceramic scaffolds for bone tissue regeneration,” Biotechnology and Bioengineering, vol. 110, no. 5, pp. 1444–1455, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. T.-M. G. Chu, J. W. Halloran, S. J. Hollister, and S. E. Feinberg, “Hydroxyapatite implants with designed internal architecture,” Journal of Materials Science: Materials in Medicine, vol. 12, no. 6, pp. 471–478, 2001. View at Publisher · View at Google Scholar · View at Scopus
  13. A. Woesz, M. Rumpler, J. Stampfl et al., “Towards bone replacement materials from calcium phosphates via rapid prototyping and ceramic gelcasting,” Materials Science and Engineering C, vol. 25, no. 2, pp. 181–186, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. H. Jiankang, L. Dichen, L. Yaxiong, Y. Bo, L. Bingheng, and L. Qin, “Fabrication and characterization of chitosan/gelatin porous scaffolds with predefined internal microstructures,” Polymer, vol. 48, no. 15, pp. 4578–4588, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. N. E. Antolino, G. Hayes, R. Kirkpatrick et al., “Lost mold rapid infiltration forming of mesoscale ceramics: part 1, fabrication,” Journal of the American Ceramic Society, vol. 92, supplement 1, pp. S63–S69, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. A. M. Morales, R. Pitchumani, T. J. Garino, A. K. Gutmann, and L. A. Domeier, “Fabrication of ceramic microstructures via microcasting of nanoparticulate slurry,” Journal of the American Ceramic Society, vol. 88, no. 3, pp. 570–578, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. T. J. Garino, A. M. Morales, and B. L. Boyce, “The mechanical properties, dimensional tolerance and microstructural characterization of micro-molded ceramic and metal components,” Microsystem Technologies, vol. 10, no. 6-7, pp. 506–509, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. M. A. Liebschner and D. H. Kim, Computer-Aided Tissue Engineering, Humana Press, Springer, New York, NY, USA, 2012.
  19. P. H. Warnke, H. Seitz, F. Warnke et al., “Ceramic scaffolds produced by computer-assisted 3D printing and sintering: characterization and biocompatibility investigations,” Journal of Biomedical Materials Research. Part B Applied Biomaterials, vol. 93, no. 1, pp. 212–217, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Schumacher, U. Deisinger, G. Ziegler, and R. Detsch, “Indirect rapid prototyping of biphasic calcium phosphate scaffolds as bone substitutes: influence of phase composition, macroporosity and pore geometry on mechanical properties,” Journal of Materials Science: Materials in Medicine, vol. 21, no. 12, pp. 3119–3127, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. K. Chopra, P. M. Mummery, B. Derby, and J. E. Gough, “Gel-cast glass-ceramic tissue scaffolds of controlled architecture produced via stereolithography of moulds,” Biofabrication, vol. 4, no. 4, Article ID 045002, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. D. Yang, H. Shao, Z. Guo, T. Lin, and L. Fan, “Preparation and properties of biomedical porous titanium alloys by gelcasting,” Biomedical Materials, vol. 6, no. 4, Article ID 045010, 2011. View at Publisher · View at Google Scholar · View at Scopus
  23. S. Padilla, J. Romàn, and M. Vallet-Regí, “Synthesis of porous hydroxyapatites by combination of gelcasting and foams burn out methods,” Journal of Materials Science: Materials in Medicine, vol. 13, no. 12, pp. 1193–1197, 2002. View at Publisher · View at Google Scholar · View at Scopus
  24. M. H. Ng, S. Duski, K. K. Tan et al., “Repair of segmental load-bearing bone defect by autologous mesenchymal stem cells and plasma-derived fibrin impregnated ceramic block results in early recovery of limb function,” BioMed Research International, vol. 2014, Article ID 345910, 11 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  25. D. Du, T. Ushida, and K. S. Furukawa, “Influence of cassette design on three-dimensional perfusion culture of artificial bone,” Journal of Biomedical Materials Research—Part B: Applied Biomaterials, vol. 103, no. 1, pp. 84–91, 2014. View at Publisher · View at Google Scholar · View at Scopus
  26. C. E. Wilson, J. D. de Bruijn, C. A. van Blitterswijk, A. J. Verbout, and W. J. A. Dhert, “Design and fabrication of standardized hydroxyapatite scaffolds with a defined macro-architecture by rapid prototyping for bone-tissue-engineering research,” Journal of Biomedical Materials Research. Part A, vol. 68, no. 1, pp. 123–132, 2004. View at Google Scholar · View at Scopus
  27. M. Schumacher, F. Uhl, R. Detsch, U. Deisinger, and G. Ziegler, “Static and dynamic cultivation of bone marrow stromal cells on biphasic calcium phosphate scaffolds derived from an indirect rapid prototyping technique,” Journal of Materials Science: Materials in Medicine, vol. 21, no. 11, pp. 3039–3048, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. V. Karageorgiou and D. Kaplan, “Porosity of 3D biomaterial scaffolds and osteogenesis,” Biomaterials, vol. 26, no. 27, pp. 5474–5491, 2005. View at Publisher · View at Google Scholar · View at Scopus
  29. D. R. Carte and W. C. Hayes, “The compressive behavior of bone as a two-phase porous structure,” Journal of Bone and Joint Surgery: Series A, vol. 59, no. 7, pp. 954–962, 1977. View at Google Scholar · View at Scopus
  30. J. Stampfl, H.-C. Liu, S. W. Nam et al., “Rapid prototyping and manufacturing by gelcasting of metallic and ceramic slurries,” Materials Science and Engineering A, vol. 334, no. 1-2, pp. 187–192, 2002. View at Publisher · View at Google Scholar · View at Scopus
  31. D. Du, K. S. Furukawa, and T. Ushida, “3D culture of osteoblast-like cells by unidirectional or oscillatory flow for bone tissue engineering,” Biotechnology and Bioengineering, vol. 102, no. 6, pp. 1670–1678, 2009. View at Publisher · View at Google Scholar · View at Scopus