Research Article
PPARα Agonist WY-14643 Induces SIRT1 Activity in Rat Fatty Liver Ischemia-Reperfusion Injury
Table 1
Effect of WY-14643 administration in hepatic injury in steatotic livers subjected to ischemia-reperfusion.
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Alanine aminotransferase (ALT) levels in plasma after 24 h of reperfusion. Sham: anesthesia and laparotomy, IR: 60 min partial ischemia and 24 h of reperfusion, and WY-14643 + IR: iv administration of WY-14643 (10 mg/kg) 1 hour before IR. versus Sham; versus IR. |