Fuzheng Huayu Recipe Ameliorates Liver Fibrosis by Restoring Balance between Epithelial-to-Mesenchymal Transition and Mesenchymal-to-Epithelial Transition in Hepatic Stellate Cells

Figure 2

Normalization of TGF-/BMP-7 ratio by FZHY recipe inhibits p38 MAPK signaling pathway in activated HSCs. (a) The mRNA expression levels of TGF-, BMP-7, and p38 MAPK in the control, model, 5% FZHY-treated, 10% FZHY-treated, and 20% FZHY-treated group, respectively. (b) Western blot of TGF, BMP-7, p38 MAPK, and p-p38 MAPK in the control, model, 5% FZHY-treated, 10% FZHY-treated, and 20% FZHY-treated group, respectively. (c) Relative protein levels of TGF, BMP-7, p38 MAPK, and p-p38 MAPK. (d) The TGF-/BMP-7 ratio at transcriptional and translational levels. compared with control group. compared with model group.

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