Fuzheng Huayu Recipe Ameliorates Liver Fibrosis by Restoring Balance between Epithelial-to-Mesenchymal Transition and Mesenchymal-to-Epithelial Transition in Hepatic Stellate Cells

Figure 3

Inactivation of p38 MAPK signaling pathway prevents EMT and induced MET of HSCs. (a) The mRNA expression levels of E-cadherin (MET specific gene), α-SMA (EMT specific gene), and desmin (EMT specific gene) in the control, model, 5% FZHY-treated, 10% FZHY-treated, and 20% FZHY-treated group, respectively. (b) Western blot of E-cadherin, α-SMA, and desmin in the control, model, 5% FZHY-treated, 10% FZHY-treated, and 20% FZHY-treated group, respectively. (c) Relative protein levels of E-cadherin, α-SMA, and desmin. compared with control group. compared with model group.

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