Trichomonas vaginalis Cysteine Proteinases: Iron Response in Gene Expression and Proteolytic Activity

Figure 5

Total EST analysis and phylogenetic tree of asparaginyl endopeptidase-like (AEP-like) CP-encoding genes expressed under different conditions. (a) Bar graph of the total ESTs found on the T. vaginalis genome database (http://www.trichdb.org/) (Total EST, orange bars) compared with the number of ESTs expressed in parasites grown under iron-restricted conditions (TvLI, blue bars) (see Table 2). (b) Phylogenetic tree of legumain-like proteins using the DNAMAN program version 3.0 and a bootstrapping of 1000. The names of known AEP-like CP-coding genes are shown.

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