Research Article

Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model

Figure 3

The relative abundance of certain cell types in the spleen and lymph nodes was altered after primary infection. Mice were infected by tail vein injection with 1 × 104 CFU/g S. aureus, a dose that caused no mortality. (a) Spleen and (b) lymph nodes were harvested on day 8 after primary infection, and their leukocyte cell type composition was analyzed by flow cytometry. Values shown are average ± SE percent of parent group, as explained in the legend for Figure 1 ( per group).