Resistance of Permafrost and Modern Acinetobacter lwoffii Strains to Heavy Metals and Arsenic Revealed by Genome Analysis

Table 2

Characteristics of ancient plasmids carrying heavy metal resistance determinants and corresponding MICs.

Strain	Plasmid [GenBank accession number]	Size of plasmid (bp)	Resistance determinants	MICs
ED23-35	pALWED1.1 KX426227	287630	Hg, Chr, Co/Zn/Cd, Ni	Hg(>0.06), As3(<5), As5(20), Cr(1.8), Co(0.1), Cd(0.025), Zn(6.4), Ni(2.7), Cu(<0.9)
	pALWED1.3 KX426228	16071	Chr
ED45-23	pALWED2.1 KX426229	190039	Hg, Ars, Cu	Hg(0.06), As3(20), As5(40), Cr(<0.3), Co(<0.05), Cd(<0.012), Zn(<0.2), Ni(<0.45), Cu(0.9)
ЕD9-5а	pALWED3.1 KX528687	138028	Hg, Ars, Co/Zn/Cd, Cu	Hg(>0.06), As3(30), As5(60), Cr(1.2), Co(<0.05), Cd(0.025), Zn(3.2), Ni(1.8), Cu(3.6)
	pALWED3.5 KX426230	16568	Chr
VS15	pALWVS1.1 KX426232	134767	Co/Zn/Cd, Cu	Hg(<0.015), As3(<5), As5(<20), Cr(<0.3), Co(0.05), Cd(0.1), Zn(3.2), Ni(0.9), Cu(3.6)
ЕК30А	pALWEK1.1 KX528688	209983	Co/Zn/Cd, Cu	Hg(<0.015), As3(<5), As5(<20), Cr(1.2), Co(0.05), Cd(0.025), Zn(<0.2), Ni(0.45), Cu(3.6)
	pALWEK1.5 KX426231	8227	Chr

The minimal inhibitory concentrations (mM) of each salt are presented in parentheses; resistance due to the presence of the relevant genes marked in bold.