Identification of ITGA2B and ITGB3 Single-Nucleotide Polymorphisms and Their Influences on the Platelet Function
Table 6
Comparison of ITGA2B and ITGB3 allele frequencies in different ethnic groups.
dbSNP
Number
This study Chinese
ITGA2B-01
rs3760364
T(0.052)
T(0.012)
T(0)
T(0)
ITGA2B-08
rs850730
G(0.477)
G(0.467)
G(0.297)
G(0.437)
ITGA2B-11
rs5911
G(0.477)
G(0.467)
G(0.305)
G(0)
ITGA2B-12
rs5910
T(0.465)
T(0.442)
T(0.376)
T(0.432)
ITGB3-03
rs7208170
A(0.419)
A(0.496)
A(0.194)
A(0.431)
ITGB3-05
rs7208055
A(0.221)
A(0.225)
A(0.117)
A(0.356)
ITGB3-06
rs55827077
C(0.448)
C(0.417)
C(0.158)
C(0.39)
ITGB3-08
rs117052258
C(0.227)
C(0.208)
NA
NA
ITGB3-10
rs11871251
A(0.453)
A(0.482)
A(0.199)
A(0.373)
ITGB3-12
rs12188890
T(0.116)
T(0)
T(0.023)
T(0)
ITGB3-16
rs1009312
G(0.417)
A(0.434)
A(0.125)
A(0.432)
ITGB3-17
rs2015049
G(0.471)
A(0.478)
A(0.138)
A(0.413)
NF.
rs5918
C(0)
C(0.007)
C(0.137)
C(0.128)
ITGB3-18
rs56197296
delTTTGT (0.169)
NA
NA
NA
ITGB3-19
rs5919
C(0.262)
C(0.232)
C(0.049)
C(0.187)
ITGB3-23
rs4642
G(0.331)
G(0.31)
G(0.283)
G(0.306)
ITGB3-25
rs4634
A(0.331)
A(0.350)
A(0.283)
A(0.331)
ITGB3-29
rs70940817
A(0.076)
NA
NA
NA
dbSNP, single nucleotide polymorphism database; MA(F), minor allele (frequency); SNP, single nucleotide polymorphisms; NF, not found; NA, not available. Resource of MP(F)s was from GenBank and HapMap, https://www.ncbi.nlm.nih.gov/snp/; Han Chinese in Beijing, China (CHB), or CHB + Japanese in Tokyo, Japan (JPT), if there is no CHB data in the SNP; Utah residents with Northern and Western European ancestry from the CEPH collection (CEU); Yoruba in Ibadan, Nigeria (YRI).
