Research Article

Comparative Genomics of H. pylori and Non-Pylori Helicobacter Species to Identify New Regions Associated with Its Pathogenicity and Adaptability

Figure 5

Regions conserved in H. pylori and absent from NHPS. From inside to outside, rings 1 and 2 are GC content and GC skew of reference genome H. pylori 26695, respectively; rings 3–7 represent H. pylori strains while rings 8–31 represent NHPS. The depth of color of rings 3–31 indicates the sequence similarity. Outer ring is the unique regions of H. pylori and absent from NHPS. Inside the outer ring, different colors represent different function categories: purple: Cag-PAI; blue: membrane genes; green: transport and metabolism genes; gray: cell growth, division, and basic metabolism; aqua: other functional genes; black: hypothetical genes; red: sRNAs.