rLj-RGD3, a Novel Three-RGD-Motif-Containing Recombinant Protein from Lampetra japonica, Protects PC12 Cells from Injury Induced by Oxygen-Glucose Deprivation and Reperfusion

Figure 7

The effect of rLj-RGD3 on PC12 cell apoptosis after OGD-R injury as indicated by flow cytometry. In Figure 7(a), (A), (B), (C), (D), (E), and (F) represent the control, model, rLj-RGD3 16, 8, and 4 μmol/L dose groups, and the edaravone control group, respectively. The bar graph showed the apoptosis rate in Figure 7(b). The numbers of apoptotic cells in the rLj-RGD3 groups were significantly lower than those of the model group. The results suggested that rLj-RGD3 had an antiapoptotic effect on PC12 cells after OGD-R. The data are shown as means ± SD, . indicates versus the control group; indicates versus the model group.

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