The Evolution of Human Basophil Biology from Neglect towards Understanding of Their Immune Functions

<div>Influence of C/EBP<i>α</i> and GATA-2 on the basophil development in spleen (left) and bone marrow (right). In the final maturation step basophils might be either elicited by IL-3 or TSLP. HSC: hematopoietic stem cell; CLP: common lymphoid progenitor; CMP: common myeloid progenitor; GMP: granulocyte/monocyte progenitor; BMCP: basophil/mast cell progenitor; pre-BMP: prebasophil mast cell progenitor; BaP: basophil progenitor; IL-3: interleukin 3; TSLP: thymic stromal lymphopoietin.</div>

BioMed Research International

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Figure 2

Figure 2: The Evolution of Human Basophil Biology from Neglect towards Understanding of Their Immune Functions 