Review Article

The Evolution of Human Basophil Biology from Neglect towards Understanding of Their Immune Functions

Figure 5

Determination of the hypoallergenic factor (here of 122) from C50 values of allergen (20.1 pg/mL, in red) versus hypoallergen (2.46 ng/mL, in blue). The experimentally determined activation values () have been approximated to analytically defined sigmoidal curves (broken lines) from which the C50 values were calculated [178].