The Association of Chemokine Gene Polymorphisms with VKH and Behcet’s Disease in a Chinese Han Population

Table 3

Genotype and allele frequencies of five chemokine genes’ polymorphism in BD and healthy controls.

Gene	SNP		BD (%)	Controls (%)	value	value	OR	95% CI
CCL5	rs2107538	Total sample	368	556
		CC	165 (0.448)	213 (0.383)	0.048	NS	1.309	1.002–1.710
		CT	155 (0.421)	272 (0.489)	0.042	NS	0.760	0.583–0.991
		TT	48 (0.130)	71 (0.128)	0.903	NS	1.025	0.692–1.517
		C	485 (0.659)	698 (0.628)	0.170	NS	1.146	0.943–1.393
		T	251 (0.341)	414 (0.372)			0.873	0.718–1.060
CCL17	rs223828	Total sample	371	604
		CC	155 (0.418)	287 (0.575)	0.081	NS	0.793	0.611–1.029
		CT	167 (0.450)	264 (0.437)	0.690	NS	1.054	0.813–1.368
		TT	49 (0.132)	53 (0.088)	0.028	NS	1.582	1.048–2.389
		C	477 (0.643)	838 (0.694)	0.020	NS	0.795	0.655–0.965
		T	265 (0.357)	370 (0.306)
CCL22	rs4359426	Total sample	365	546
		AA	14 (0.038)	7 (0.013)	0.012	NS	3.071	1.227–7.685
		AC	93 (0.255)	134 (0.245)	0.749	NS	1.051	0.774–1.427
		CC	258 (0.707)	405 (0.742)	0.246	NS	0.839	0.624–1.128
		A	121 (0.166)	148 (0.136)	0.075	NS	1.267	0.976–1.645
		C	609 (0.834)	944 (0.864)			0.789	0.608–1.024
CXCL10	rs2869462	Total sample	360	535
		CC	149 (0.414)	184 (0.344)	0.034	NS	1.347	1.023–1.774
		CG	160 (0.444)	243 (0.454)	0.773	NS	0.961	0.735–1.258
		GG	51 (0.142)	108 (0.202)	0.210	NS	0.653	0.454–0.939
		C	458 (0.636)	611 (0.571)	0.006	NS	1.313	1.081–1.595
		G	262 (0.364)	459 (0.429)			0.761	0.627–0.925
CXCL12	rs1801157	Total sample	371	547
		CC	207 (0.558)	271 (0.495)	0.063	NS	1.285	0.987–1.675
		CT	139 (0.375)	241 (0.441)	0.047	NS	0.761	0.581–0.996
		TT	25 (0.067)	35 (0.064)	0.838	NS	1.057	0.621–1.798
		C	553 (0.745)	783 (0.716)	0.163	NS	1.162	0.941–1.435
		T	189 (0.255)	311 (0.284)			0.860	0.697–1.063