The Association of Chemokine Gene Polymorphisms with VKH and Behcet’s Disease in a Chinese Han Population

Table 4

Genotype and allele frequencies of three chemokine genes’ polymorphism in VKH and healthy controls.

Gene	SNP		VKH (%)	Controls (%)	value	value	OR	95% CI
CCL5	rs9355610	Total sample	370	555
		AA	97 (0.262)	138 (0.249)	0.644	NS	1.074	0.794–1.451
		AG	188 (0.508)	273 (0.492)	0.629	NS	1.067	0.820–1.388
		GG	85 (0.230)	144 (0.259)	0.305	NS	0.851	0.626–1.158
		A	282 (0.516)	549 (0.495)	0.029	NS	0.805	0.662–0.979
		G	358 (0.484)	561 (0.505)			1.242	1.022–1.511
CXCL8	rs2227543	Total sample	364	552
		CC	146 (0.401)	187 (0.339)	0.055	NS	1.307	0.994–1.719
		CT	155 (0.426)	280 (0.507)	0.016	NS	0.720	0.552–0.940
		TT	63 (0.173)	85 (0.154)	0.442	NS	1.15	0.805–1.643
		C	447 (0.614)	654 (0.592)	0.355	NS	1.095	0.904–1.326
		T	281 (0.386)	450 (0.408)			0.914	0.754–1.106
CXCL12	rs1801157	Total sample	368	547
		CC	223 (0.605)	271 (0.495)	0.001	NS	1.566	1.198–2.048
		CT	122 (0.331)	241 (0.441)		NS	0.637	0.478–0.829
		TT	23 (0.062)	35 (0.064)	0.928	NS	0.975	0.566–1.679
		C	568 (0.771)	783 (0.716)	0.008	NS	1.343	1.081–1.668
		T	168 (0.228)	311 (0.284)			0.745	0.600–0.925