Automated Image Analysis of HER2 Fluorescence In Situ Hybridization to Refine Definitions of Genetic Heterogeneity in Breast Cancer Tissue

Figure 3

A bubble plot of the clusters obtained from the factor 1, 2, and 3 scores. Cluster colors: Cluster 1, red; Cluster 2, orange; Cluster 3, blue; and Cluster 4, purple. Bubble size represents factor 3 (bimodality); center is empty for negative and filled for positive values. Numbers indicate cluster examples depicted in Figure 4.