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BioMed Research International
Volume 2017, Article ID 3072098, 6 pages
Review Article

Treatment of Cervical Artery Dissection: Antithrombotics, Thrombolysis, and Endovascular Therapy

1Department of Neurology of Southwest Hospital, Third Military Medical University, No. 30 Gaotanyan Road, Chongqing 400038, China
2Department of Neurology, China-Japan Friendship Hospital, 2 Yinghua Dongjie, Hepingli, Beijing 100029, China

Correspondence should be addressed to Zhenhua Zhou; moc.621@100retiolpxe

Received 31 January 2017; Revised 23 March 2017; Accepted 16 April 2017; Published 21 May 2017

Academic Editor: Sheng Chen

Copyright © 2017 Jing Peng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Cervical artery dissection (CAD) is an important cause of stroke for young patients, accounting for 5–22% of strokes in patients <45 years of age, which presents not only a great burden to the stroke victims but also a financial burden to the family and society. Because CAD can lead to different clinical lesions, including neuropathy, acute ischemic stroke, and subarachnoid hemorrhage, and is an arterial dissection with a self-healing tendency, the treatment options depend on the clinical manifestations. The main purpose of the treatment is to control CAD-induced neuronal damage and to restore blood flow. The treatment programs include drug treatment and endovascular treatment. However, antithrombotic treatment is crucial. Both antiplatelet drugs and anticoagulant drugs are used to reduce the risk of stroke, but whether one treatment strategy is more effective than the other is unknown. The efficacy and timing of the endovascular treatment of CAD remain controversial.