Stroke is when poor blood flow to the brain results in cell death. There are two main types of stroke: ischemic and hemorrhagic. While ischemic strokes account for the majority of strokes, hemorrhagic stroke is more deadly which poses a public health threat, caused by a blood vessel in the brain leaking and rupturing blood. According to the National Stroke Association, about 795,000 people fall victim to a stroke annually, with 160,000 of those people becoming a fatality statistic. There are several types of hemorrhagic stroke, such as intracerebral hemorrhage, aneurysmal subarachnoid hemorrhage, arteriovenous malformation bleeding, and cerebral amyloid angiopathy.

Recent advances in the molecular and cellular mechanisms underlying the pathogenesis of hemorrhagic stroke have allowed for a better understanding of the disease mechanisms. In addition, the progress in clinical studies includes updated guideline, advanced technique, and new pharmaceutical drug. The purpose of special issue is to provide an up-to-date overview of the physiology, pharmaceutical drug, and management of hemorrhagic stroke. Original, high-quality research papers as well as review articles addressing the major research challenges and achievements on the topic are sought.

Potential topics include but are not limited to the following:

• New pharmaceutical drug
• Clinical guidelines
• Epidemiological and clinical studies
• Neuroimaging study
• Neuropathological assessment
• Neurobehavioral aspects
• Pathophysiology study
• Translational study
• Clinical trials
• Prospective of hemorrhagic stroke