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BioMed Research International
Volume 2017, Article ID 5135429, 18 pages
Review Article

Preclinical Studies and Translational Applications of Intracerebral Hemorrhage

1Department of Neurosurgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China
2Zhejiang Provincial Key Laboratory of Aging and Neurological Disorder Research, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325000, China

Correspondence should be addressed to Qichuan Zhuge; moc.361.piv@nauhciqeguhz and Lijie Huang; moc.361@ywgnauheijil

Received 23 February 2017; Revised 16 April 2017; Accepted 2 May 2017; Published 18 June 2017

Academic Editor: John H. Zhang

Copyright © 2017 Felix Siaw-Debrah et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Intracerebral hemorrhage (ICH) which refers to bleeding in the brain is a very deleterious condition with high mortality and disability rate. Surgery or conservative therapy remains the treatment option. Various studies have divided the disease process of ICH into primary and secondary injury, for which knowledge into these processes has yielded many preclinical and clinical treatment options. The aim of this review is to highlight some of the new experimental drugs as well as other treatment options like stem cell therapy, rehabilitation, and nanomedicine and mention some translational clinical applications that have been done with these treatment options.