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BioMed Research International
Volume 2017 (2017), Article ID 6138424, 11 pages
Review Article

White Matter Injury and Recovery after Hypertensive Intracerebral Hemorrhage

Department of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, China

Correspondence should be addressed to Yujie Chen

Received 9 February 2017; Accepted 7 May 2017; Published 7 June 2017

Academic Editor: Gang Chen

Copyright © 2017 Shilun Zuo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Hypertensive intracerebral hemorrhage (ICH) could very probably trigger white matter injury in patients. Through the continuous study of white matter injury after hypertensive ICH, we achieve a more profound understanding of the pathophysiological mechanism of its occurrence and development. At the same time, we found a series of drugs and treatment methods for the white matter repair. In the current reality, the research paradigm of white matter injury after hypertensive ICH is relatively obsolete or incomplete, and there are still lots of deficiencies in the research. In the face of the profound changes of stroke research perspective, we believe that the combination of the lenticulostriate artery, nerve nuclei of the hypothalamus-thalamus-basal ganglia, and the white matter fibers located within the capsula interna will be beneficial to the research of white matter injury and repair. This paper has classified and analyzed the study of white matter injury and repair after hypertensive ICH and also rethought the shortcomings of the current research. We hope that it could help researchers further explore and study white matter injury and repair after hypertensive ICH.