Evaluation of Plasma MicroRNAs as Diagnostic and Prognostic Biomarkers in Pancreatic Adenocarcinoma: miR-196a and miR-210 Could Be Negative and Positive Prognostic Markers, Respectively

Table 3

Univariate survival analysis of conventional prognostic factors based on the characteristics of the PDAC patients corresponding to the survival time.

Characteristic	Number	Median survival (month)	value
Gender			0.550
Male	20	7.0
Female	11	8.7
Age (years)			0.521
≥60	17	10.7
<60	14	6.9
Cigarette smoking			0.255
Yes	10	6.5
No	21	7.5
Alcohol consumption			0.154
Yes	10	7.0
No	21	8.1
Abdominal pain			0.341
Yes	13	6.8
No	18	8.1
Jaundice			0.058
Yes	9	6.9
No	22	9.9
Tumor location			0.531
Head and neck	26	6.1
Body and tail	5	8.8
Operation method			0.009
Radical surgery	9	11.2
Palliative surgery	17	6.3
No surgery	5	5.5
Tumor size (cm)			0.289
≤2	4	9.3
>2–≤4	18	10.1
>4	9	6.7
Lymph node metastasis			0.001
Yes	19	5.0
No	12	12.5
Serosal infiltration			0.002
Yes	20	7.0
No	11	13.2
Vessel infiltration			0.053
Yes	17	6.8
No	14	9.5
Comprehensive therapy			0.024
Yes	19	10.4
No	12	6.9
Distant metastasis			0.079
Yes	6	6.8
No	25	8.1