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BioMed Research International
Volume 2017 (2017), Article ID 7859719, 5 pages
Clinical Study

Medical and Interventional Therapy for Spontaneous Vertebral Artery Dissection in the Craniocervical Segment

1Department of Neurosurgery, Shanghai Jiaotong University First People’s Hospital, Shanghai 200080, China
2Department of Neurosurgery, Tenth People’s Hospital of Tongji University, Shanghai 200072, China

Correspondence should be addressed to Zuoquan Chen

Received 21 December 2016; Accepted 31 January 2017; Published 22 February 2017

Academic Editor: John H. Zhang

Copyright © 2017 Guiyun Zhang and Zuoquan Chen. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background and Purpose. Spontaneous vertebral artery dissection (SVAD) is an important reason for posterior-circulation-ischemic stroke in the young and middle-aged population. Although some previous reports reveal a favorable outcome with conservative therapy, it is still controversial in the treatment of SVAD in some specific patients. Herein, we present our 10 years of clinical experience for SVAD at this location. Material and Methods. 20 patients with 20 SVADs in V2 and V3 segments were retrospectively studied. Clinical manifestations and imageology materials were collected and analyzed. All the patients underwent anticoagulation except for one patient because of contraindication. 14 patients underwent Wingspan stents implantation with general anesthesia. Results. In our sample, ischemia (infarction or transient ischemic attack, TIA) was found in all the patients. Angiographic stenosis and dissection aneurysm were the most common findings in the segments mentioned above. 19 of the patients (95%) got the excellent imageological and clinical outcomes. Conclusions. According to our experience in this group, although anticoagulation is effective in vertebral artery dissection, interventional therapy for SVADs in V2 and/or V3 segments is preferred in some specific patients. Stent with higher radial supporting and flexibility, such as Wingspan stent, is suggested.