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Research Article
BioMed Research International
Volume 2017, Article ID 9496485, 1 page
https://doi.org/10.1155/2017/9496485
Retraction

Retracted: Tanshinone IIA Induces Apoptosis in Human Oral Cancer KB Cells through a Mitochondria-Dependent Pathway

BioMed Research International

Received 29 October 2017; Accepted 29 October 2017; Published 21 November 2017

Copyright © 2017 BioMed Research International. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


BioMed Research International has retracted the article titled “Tanshinone IIA Induces Apoptosis in Human Oral Cancer KB Cells through a Mitochondria-Dependent Pathway” [1]. As noted by Amanda Capes-Davis on PubMed Commons, KB cells are cross-contaminated by HeLa and are not oral cancer cells [2]. Therefore, the conclusions cannot be supported. Tan IIA was already known to induce apoptosis in HeLa cells through a mitochondria-dependent pathway [3].

References

  1. P.-Y. Tseng, W.-C. Lu, M.-J. Hsieh, S.-Y. Chien, and M.-K. Chen, “Tanshinone IIA induces apoptosis in human oral cancer KB cells through a mitochondria-dependent pathway,” BioMed Research International, vol. 2014, Article ID 540516, 7 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  2. T. Chen, “Modal karyotype of human leukemia cell line, K562 (ATCC CCL 243),” Cancer Genetics and Cytogenetics, vol. 17, no. 1, pp. 55–60, 1985. View at Publisher · View at Google Scholar
  3. L. Zhou, W. K. Chan, N. Xu et al., “Tanshinone IIA, an isolated compound from Salvia miltiorrhiza Bunge, induces apoptosis in HeLa cells through mitotic arrest,” Life Sciences, vol. 83, no. 11-12, pp. 394–403, 2008. View at Publisher · View at Google Scholar · View at Scopus