BioMed Research International has retracted the article titled “Tanshinone IIA Induces Apoptosis in Human Oral Cancer KB Cells through a Mitochondria-Dependent Pathway” [1]. As noted by Amanda Capes-Davis on PubMed Commons, KB cells are cross-contaminated by HeLa and are not oral cancer cells [2]. Therefore, the conclusions cannot be supported. Tan IIA was already known to induce apoptosis in HeLa cells through a mitochondria-dependent pathway [3].
Retraction | Open Access
Retracted: Tanshinone IIA Induces Apoptosis in Human Oral Cancer KB Cells through a Mitochondria-Dependent Pathway
Received29 Oct 2017
Accepted29 Oct 2017
Published21 Nov 2017
References
P.-Y. Tseng, W.-C. Lu, M.-J. Hsieh, S.-Y. Chien, and M.-K. Chen, “Tanshinone IIA induces apoptosis in human oral cancer KB cells through a mitochondria-dependent pathway,” BioMed Research International, vol. 2014, Article ID 540516, 7 pages, 2014.
View at: Publisher Site | Google ScholarT. Chen, “Modal karyotype of human leukemia cell line, K562 (ATCC CCL 243),” Cancer Genetics and Cytogenetics, vol. 17, no. 1, pp. 55–60, 1985.
View at: Publisher Site | Google ScholarL. Zhou, W. K. Chan, N. Xu et al., “Tanshinone IIA, an isolated compound from Salvia miltiorrhiza Bunge, induces apoptosis in HeLa cells through mitotic arrest,” Life Sciences, vol. 83, no. 11-12, pp. 394–403, 2008.
View at: Publisher Site | Google Scholar
Copyright
Copyright © 2017 BioMed Research International. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.