Protein Arginine Methyltransferase 2 Inhibits Angiotensin II-Induced Proliferation and Inflammation in Vascular Smooth Muscle Cells

Figure 4

PRMT2 overexpression suppressed Ang II-induced VSMCs inflammation. After transfection with pcDNA3.1-PRMT2 for 24 hours, VSMCs were treated with 100 nM Ang II for 24 hours. (a) IL-1β protein level. (b) IL-6 protein level. Ang II represents angiotensin II; VSMCs represent vascular smooth muscle cells. P<0.05 versus vector group, ^#P<0.05 versus Ang II group. n=3 independent experiments.

(a)

(b)