Simvastatin Improves the Jaw Bone Microstructural Defect Induced by High Cholesterol Diet in Rats by Regulating Autophagic Flux

Figure 3

Effects of simvastatin on the NF-κB signaling in the jaw bone of HC rats. HCD feeding increased the levels of NF-κB signaling in the jaw bone tissues. Simvastatin reduced the one. (a) NF-κB gene expression. (b) NF-κB protein expression in NC (c), HC (d), and HC+SIM (e) (magnification, 400). NC: normal control diet; HC: high cholesterol diet; HC+SIM: high cholesterol diet + simvastatin; ; ; .

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