Differentiation Model Establishment and Differentiation-Related Protein Screening in Primary Cultured Human Sebocytes

Figure 3

Proteome alterations during human sebocyte differentiation in vitro. Human primary sebocytes were induced to differentiate by serum deprivation. These cells were harvested at days 0, 1, 3, 5, and 7 and then subjected to the iTRAQ-based quantitative proteomic analysis. Numbers of up- and downregulated proteins in differentiated sebocytes at days 1, 3, 5, and 7 were shown. The expression profile of cells at day 0 was used as a control.