Transcription Factor IRF4 Dysfunction Affects the Immunosuppressive Function of Treg Cells in Patients with Primary Immune Thrombocytopenia

Figure 5

Abnormal metabolism of Treg and Teff cells in ITP patients. (a) The oxygen consumption rate (OCR) of Treg cells in ITP and NC groups. (b) OCR of Teff cells in ITP and NC groups. (c) The extracellular media acidification rate (ECAR) of Teff cells in ITP and NC groups. (d) ECAR of Treg cells in ITP and NC groups. (e) The ratio of oxygen consumption to lactate production (OCR/ECAR) of Tregs in ITP and NC groups. (f) The ratio of OCR/ECAR of Teff cells in ITP and NC groups. p < 0. 05; p < 0. 01; p < 0. 001.

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